TXN and amebic dysentery: Jeelani and Nozaki [162] reported that Entamoeba histolytica, an intestinal parasite, causes amebic dysentery, lacks eukaryotic antioxidative defense systems but owns an efficient thioredoxin system, composed of thioredoxin and thioredoxin reductase, both are crucial for antioxidant activity and sustaining cellular redox balance [162].