It has also been suggested that monitoring KL-6 values in cases of COVID-19 ARDS might help to distinguish between patients with preserved lung compliance (type L) and patients with low lung compliance (type H), since KL-6 correlates with type II pneumocytes impairment and loss of lung elastance, thus allowing the clinicians to predict the response to mechanical ventilation [37]. This evidence concerns the gene MUC1 and acute respiratory distress syndrome.