In addition to diagnosis under surveillance (odds ratio [OR] = 1.681, 95% CI 1.445–1.956; p < 0.0001), several other variables resulted associated (p ≤ 0.10) with the survival group at the univariate logistic regression analysis: Age, overweight, cirrhosis, presence of MAFLD, ECOG-PS, CSPH, MELD score, Child-Pugh class, multifocality, tumor size, MVI, EHS, AFP, ITA.LI.CA stage, “volume” of the ITA.LI.CA Institution, and main treatment. The gene discussed is AFP; the disease is Cirrhosis.