IFNA1 and COVID-19: Such a mechanism would, not incidentally, address an ongoing criticism of the role of cytokine storms in severe COVID-19, which is that severe COVID-19 is not actually a cytokine release syndrome, since IFN is severely impaired, but, actually, an immunosuppressive disease in which the virus is enabled to spread to, and replicate in, an uncontrolled fashion in multiple organ systems [198].