Silva et al. [95] found no changes in the protein expression of TLR2, TLR4 or TLR9 and the upregulation of TLR5 in human sepsis patients, while Härter et al. [96] reported that TLR2 and TLR4 were the main receptors upregulated during sepsis, a finding confirmed by Gao et al. [97] and Kumar [98] in their patients, who also found increased expression of TLR3 and TLR7. Here, TLR4 is linked to Sepsis.