Since TENM4 has proven to be functionally related to Focal Adhesion Kinase (FAK) both in non-transformed [21,27] and in cancer cells [28], and increased expression of FAK has been reported to be an important feature of cells with a stem-like phenotype [29], we investigated FAK expression in TNBC epithelial cells and tumorspheres. This evidence concerns the gene TENM4 and cancer.