miR-3619 prevented β-catenin accumulation in the cytoplasm or its translocation into the nucleus in BLCA cells, and its overexpression enhanced E-cadherin, the epithelial biomarker, but suppressed expression of mesenchymal biomarkers Vimentin, Snail, and N-cadherin. This evidence concerns the gene CDH2 and bladder transitional cell carcinoma.