IL6 and cancer: Eosinophils and platelets have shown to be promoters of cancer progression and metastasis via the secretion of several cytokines such as interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) (responsible for a subverted host response to inflammation-induced tumors) and through platelet β3 integrins, which are particularly active in the process of bone dissemination [31,32].