This p53-association holds when IDWAS was performed on the pan-cancer TCGA with tissue type correction (n = 9968, FDR = 2.1 × 10−8) as well as in TCGA breast cancer with correction for PAM50 subtype (n = 1098, FDR = 1.6 × 10−9). The gene discussed is TP53; the disease is breast carcinoma.