Zhao et al. utilizing Dex resistant (MM1R) and sensitive MM cell line (MM1S) demonstrated that the expression of miRNAs-221/222 was increased in GC-resistant cell lines and augmented MM cell survival through Bcl2 associated X/BCL2 antagonist/killer 1/BCL2 binding component 3. The gene discussed is BCL2; the disease is Miyoshi myopathy.