Using immunofluorescence assays, it was found that the CD63 and CD151 C-terminal peptides decreased the disassembly of HPV16 capsids, which consequently inhibited infection, and that the inhibitory effect of C-terminal CD63 and CD151 peptides occurs prior to HPV capsid disassembly conforming to the role of CD63 and CD151 during HPV entry (Figure 1) [67]. The gene discussed is CD63; the disease is infection.