Further, Bauer et al. showed the ROC AUC of plasma calprotectin with regards to multiple organ failure within 72 h as (calprotectin = 0,87, lactate = 0.79, CRP = 0.70, 0.75) and ICU admission as (calprotectin = 0.70, lactate = 0.80, CRP = 0.66, PCT = 0.60) [27]. The gene discussed is CRP; the disease is Multiple Organ Failure.