Therefore, we immunolocalized CCL5, CCR1, 3 and 5 in 111 human breast carcinoma tissues and examined the significance of CCL5 in stromal cells and CCR1, 3, and 5 in tumor cells in order to better understand in more detail the clinical and/or biological significance of the CCL5/receptors axis in breast cancer. This evidence concerns the gene CCL5 and breast carcinoma.