Chemokines have important roles in the interactions between carcinoma cells and stromal cells in the tumor microenvironment, and CCL5, a member of chemokine family, is expressed in many stromal cells, such as macrophages [8,9,10,13], fibroblasts [11,18,19], lymphocytes [12] and adipocytes [14], in various types of cancers. The gene discussed is CCL5; the disease is cancer.