In the CCR1-negative/CCR3-positive/CCR5-negative group, CCL5 immunoreactivity was significantly correlated with the pT, histological grade, Ki67 LI and MVD and tended to be correlated with lymph node metastasis while negatively correlated with the ER and PR. The gene discussed is CCR5; the disease is metastatic malignant neoplasm in the lymph nodes.