CCR5 has been reported to regulate p53 transcriptional activity in breast carcinoma cells and suppress the progression of breast cancer in a p53-dependent manner by in vitro and in vivo experiments [16], and the authors also found out that the breast cancer patients with the nonfunctional CCR5∆32 allele showed shorter disease-free survivals compared to those with the wild type. Here, TP53 is linked to breast carcinoma.