ACE and hypertensive disorder: The 2017 American College of Cardiology/American Heart Association guidelines for high blood pressure for adults recommend diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), and calcium channel blockers (CCBs) as primary agents and beta blockers (BBs) and alpha blockers as secondary agents for hypertension treatment in cases without compelling indications, such as heart failure, kidney disease, and angina [1].