At the 2020 American Society of Clinical Oncology (ASCO) congress, results from the DESTINY-Lung 01 trial, a multicenter, phase II study, investigating the novel ADC trastuzumab deruxtecan (T-DXd) in patients with HER2-mutated NSCLC have been presented [198]. Here, ERBB2 is linked to non-small cell lung carcinoma.