Subsequent analysis on FaDu and Detroit562 cell lines focused on changes in the expression of genes associated with: (1) pluripotency (NANOG, SOX2, POU5F, SNAIL); (2) cell division (FOLR1); (3) proliferative activity of tumor cells (MKI67); (4) angiogenesis (VEGFA); (5) acquisition of autonomous proliferative signalling (EGFR, EGF); (6) immune response (COX2, CCL2, IL6, EP3, PGE2S); and (7) cell cycle, and cell death modifications (BCL2, BIRC5, NFKB1, CAV1). The gene discussed is FOLR1; the disease is neoplasm.