In addition, Fares-Gusmao et al. [13] identified a common immune signature for asymptomatic infections with DENV, WNV and ZIKV that included increased levels of IL-12, IL-17, IL-5, IL-10, CXCL9, E-Selectin and ST2/IL-1R4 as well as decreased levels of IL-13 and CD40 when compared to controls. Here, CD40 is linked to infection.