SERPINE1 and Hyperglycemia: ALDO showed more pronounced effects on TF (p < 0.01), t-PA (p < 0.05), PAI-1 (p < 0.01), NO2/NO3 (p < 0.01), eNOS expression (p < 0.01), H2O2 (p < 0.05), and MDA (p < 0.001) in hyperglycemia (Table 3).