AKT1 and cancer: Resveratrol (3,4′,5-trihydroxy-trans-stilbene) anti-cancer effects include anti-proliferation, cell cycle arrestment, and apoptosis promotion through multiple signaling pathways such as EGFR, p53, P13K/AKT/mTOR, STAT3, NF-κB, and oncogenic miRNAs [296,297].