ACE2 and COVID-19: For the reported inhibitor of ACE2, including MLN-4760 and DX600 (Supplementary Materials, Figure S1D,E), we also found that the MLN-4760 could bind to ACE2 at the COVID-19 virus spike receptor binding domain with the -CDocker energy (Score) of 21.028 kcal/mol (Supplementary Materials, Table S2; Figure S2A–E).