Here, the authors reported the association of dysbiotic changes, like reduction in the butyrate producers Ruminococcaceae and Butyricimonas, and the increase in Actinobacteria, Clostridium, and the proinflammatory colorectal cancer-related microbiota Veillonella with the high expression of colorectal cancer-related genes such as lipocalin 2 (LCN2) and dual oxidase 2 (DUOX2) [51]. The gene discussed is LCN2; the disease is colorectal cancer.