In this manner, a study showed that cancer-associated fibroblasts (CAFs)-derived exosomes induced endometrial cancer progression partially due to the loss of miR-148b in the exosomes, which is an important tumor suppressor by targeting DNA (cytosine-5) methyltransferase 1 (DNMT1) to suppress endometrial cancer metastasis. Here, DNMT1 is linked to cancer.