LDLR and polycystic ovary syndrome: Additionally, a recent study reported that HFF exosomes from PCOS patients had a different expression level of circRNAs, among which hsa-circ-0006877 was processed from its parental low-density lipoprotein receptor (LDLR) gene, and its depletion was evaluated to be connected to a higher expression of miR-1294 and a lower expression of cytochrome P450 family 19 subfamily A member 1 (CYP19A1).