PD is characterized by the progressive reduction of dopamine levels in the substantia nigra, degeneration of dopaminergic neurons and the formation of intracytoplasmic α-synuclein protein aggregates, known as Lewy bodies, which lead to clinical motor symptoms such as tremors, muscle stiffness, akinesia and bradykinesia, as well as cognitive impairment [7]. The gene discussed is SNCA; the disease is Parkinson disease.