Analysis of Matrigel proteolysis revealed that both breast (Figure 3B, left panel) and prostate (Figure 3B, right panel) cancer cell lines responded similarly to β1-integrin activation (P4G11 antibody) or inhibition (P5D2 antibody) alone and in combination with the inhibition of ILK (Cpd22, 5 μM) or NHE1 (cariporide, 5 μM). Here, SLC9A1 is linked to cancer.