AAs suppress the growth of the new tumour vasculature through the inhibition of vascular endothelial growth factor (VEGF) and other pro-angiogenic molecules [3,124], whereas VDAs act on endothelial cells and pericytes of the existent tumoral vasculature and consequently vessel occlusion, shutdown of the circulation and pervasive necrosis are induced inside the tumour [3,125]. Here, VEGFA is linked to neoplasm.