In the same study, AEG-1 protein expression was analyzed by IHC in 74 distant normal colorectal mucosa, 107 adjacent normal colorectal mucosa, 158 primary CRC, 35 lymph node metastases and 9 liver metastases showing significantly higher AEG-1 protein level in primary CRC samples compared to adjacent or distant normal mucosa [82]. The gene discussed is MTDH; the disease is colorectal carcinoma.