Increased AEG-1 expression correlated with differentiation degree (p = 0.0259), Nevin stage (p = 0.0339), liver infiltration (p = 0.0328) and Ki-67 expression (p = 0.0032), but did not correlate with age, gender, tumor location, tumor size, venous invasion, lymph node metastasis or pathological type [94]. The gene discussed is MTDH; the disease is neoplasm.