FFPE sections from 168 ESCC patients, which include 9 stage I, 73 stage IIa, 14 stage IIb, 62 stage III and 10 stage IV cancer, were analyzed by IHC revealing 92.9% AEG-1-positive cases and AEG-1 expression was upregulated in tumor tissues compared to adjacent non-tumor tissues [73]. Here, MTDH is linked to esophageal squamous cell carcinoma.