In addition, polymorphisms in AEG-1 gene, such as a C/T variant in exon 11 or a G>A variant in exon 9, have been shown to confer susceptibility to breast and ovarian cancers in women from specific ethnic groups in China, which needs to be validated in more extensive studies in other patient cohorts [46,47]. This evidence concerns the gene MTDH and ovarian carcinoma.