AEG-1 expression strongly correlated with lymph node metastasis (N classification; p = 0.015), distant metastasis (p = 0.004) and pathological differentiation (p = 0.027) and correlated inversely with overall survival time (p < 0.001; correlation coefficient −0.341) [39]. Here, MTDH is linked to metastatic malignant neoplasm in the lymph nodes.