AEG-1 mRNA analysis in 30 paired gastric tumor and non-tumor samples from Iranian patients identified significant overexpression of AEG-1 in tumor tissue (p = 0.05) although the expression levels showed heterogeneity, so that 46.6% cases showed higher AEG-1 and 36.6% cases showed lower AEG-1 levels in tumor tissues compared to non-tumor tissue [78]. This evidence concerns the gene MTDH and gastric neoplasm.