KEGG analysis implicates specific cancers (bladder cancer, colorectal cancer, pancreatic cancer, prostate cancer and more), along with canonical pathways such as the MAPK signaling pathway, Notch p53 signaling pathway, Wnt signaling pathway and, again, transcriptional misregulation in cancer (Figure 5A). The gene discussed is TP53; the disease is familial pancreatic carcinoma.