In a BLM mouse model of pulmonary fibrosis, BLM binding with ANXA2 impedes transcription factor EB (TFEB)-induced autophagic flux [27]; the inhibition of profibrotic cytokines induces autophagy flux and decreases the production of collagen to alleviate pulmonary fibrosis [28]. Here, TFEB is linked to pulmonary fibrosis.