In line with our findings, Bime et al. identified MIF as one out of six biomarkers (angiopoietin-2, MIF, IL-8, IL-1 receptor antagonist, IL-6, and extracellular nicotinamide phosphoribosyltransferase) and, when combined, as a strong predictor of 28-day mortality in ARDS patients [27]. This evidence concerns the gene ANGPT2 and acute respiratory distress syndrome.