TP53 and Duchenne muscular dystrophy: The tumorigenic potential of SCs in promoting eRMS was also investigated through a mouse model of Duchenne muscular dystrophy (DMD) lacking Tp53 gene (Tp53KOmdx/mTR), demonstrating that the DMD severity reduced the latency of RMS formation and increased the ability of SCs to develop rhabdomyosarcomas when injected into immunodeficient mice [58].