So, the objective of this study was to describe and compare the allelic and genotypic frequencies of the rs524952, rs8000973, rs1881492, rs1656404, rs235770, and rs7744813 SNPs of the GJD2, ZIC2, CHRNG, PRSS56, BMP2, and KCNQ5 genes, respectively, between responder and nonresponder patients who had undergone a two-year treatment with lenses for myopia control. The gene discussed is GJD2; the disease is myopia.