These cDC1 cells in turn secrete Chemokine (C-X-C motif) ligand 9 (CXCL9) and Chemokine (C-X-C motif) ligand 10 (CXCL10), two IFN-γ-driven chemokines, leading to the recruitment of CXCR3+ effector NK and CD8+ T cells, that may further produce IFN-γ and generate anti-tumor inflammatory responses in a self-amplifying positive feedback loop (Figure 3) [71]. This evidence concerns the gene IFNG and neoplasm.