In 2020, Lyons J.J. et al. described a significantly higher prevalence of HαT in patients with idiopathic anaphylaxis (17–8/47) compared to a HαT prevalence of 5.6% in healthy individuals (7/125) and in controls with nonatopic disease (5.3%; 21/398). This evidence concerns the gene TMPRSS11D and anaphylaxis.