This IR-sensitization capacity of EphA2 ablation was evident in NSCLC cell lines of different histology and also in cells with mutant EGFR. These data on a role of EphA2 per se in the regulation of NSCLC cell survival are in line with earlier reports [26,27,28,31,32]. This evidence concerns the gene EPHA2 and non-small cell lung carcinoma.