Up regulated genes in the pAT, identified amongst the 770 cancer-related genes included in the nCounter PanCancer Panel, were involved in the phosphatidylinositol-3-kinase (PI3K)-Akt signalling, focal adhesion, ECM-receptor interaction, mitogen-activated protein kinase (MAPK) signalling, Ras signalling, Wnt signalling, and Hippo signalling pathway (Supplementary Table S2). Here, AKT1 is linked to cancer.