Yet, only the cells from Majeed syndrome patients (versus NOMID or healthy controls) showed increased expression of osteoclastogenic mediators including IL-8, IL-6, TNF, CCL2, MIP1α, MIP-1β, CXCL8/IL-8 and CXCL1 in M2-like macrophages stimulated with LPS [81]. The gene discussed is TNF; the disease is Majeed syndrome.