ZMYND8 knockdown increases the expression of Ki67 and PCNA by about 14 and 4 folds, respectively, in HeLa cells; about 8 and 3 folds in MCF7 breast cancer cells; and about 9 and 2.5 folds in T47D metastatic breast cancer cells [10]. This evidence concerns the gene ZMYND8 and breast cancer.