The noted upregulation of GGPS1 and FDPS is an important observation in the context of breast cancer pathogenesis as these enzymes are components of the mevalonate pathway with role in cholesterol biosynthesis and bone metastasis of breast cancer, prostate cancer, and multiple myeloma [39,40,41,42,43,44]. This evidence concerns the gene GGPS1 and Familial prostate cancer.