The noted upregulation of GGPS1 and FDPS is an important observation in the context of breast cancer pathogenesis as these enzymes are components of the mevalonate pathway with role in cholesterol biosynthesis and bone metastasis of breast cancer, prostate cancer, and multiple myeloma [39,40,41,42,43,44]. The gene discussed is GGPS1; the disease is prostate carcinoma.