STS and recessive X-linked ichthyosis: Two cases with 22q.11.2 deletion syndrome (Case s-12 and Case s-18), a case with 22q.11.2 duplication syndrome (Case s-1), a case with steroid sulfatase (STS) deficiency (Case s-2), and a structural anomaly (Case s-17) were diagnosed as pathogenic, and the other 13 cases resulted in VUS or were benign.