INS and polycystic ovary syndrome: Since the 1RC group included both women with and without hyperandrogenemia (which might explain the not significant OR for phenotype analysis), we performed Spearman correlation analyses in women with HA comparing our four main glucose metabolism parameters (HOMA, Matsuda, glucose area-under-the-curve (AUC) and insulin AUC) with our hormones and metabolic parameters (Table S2).