ENG and myocardial infarction: Furthermore, Eng+/− reduced myocardial repair after experimentally induced myocardial infarction (MI) [5], and systemic application of wild type mononuclear cells (MNCs) stimulated revascularization of the injured myocardium and restored cardiac recovery of Eng+/− mice, an effect not seen when MNCs of HHT1 patients were used [5].