CD8A and neoplasm: The number of tumour-infiltrating cells stained with the T cell marker CD3 (anti-CD3-Alexa-546), the T helper cell marker, CD4 (anti-CD4-Alexa-488), and the cytotoxic T cell marker CD8 (anti-CD8-Alexa-633) all showed a small but significant decrease in immune infiltration into tumours isolated from mice treated with Uncaria tomentosa extracts compared to animals injected with the vehicle only (Figure 7).