CD4 and neoplasm: The number of tumour-infiltrating cells stained with the T cell markers CD3 (anti-CD3-Alexa-546), CD4 (anti-CD4-Alexa-488), and CD8 (anti-CD8-Alexa-633) were all decreased by about 10% in tumours isolated from mice treated with Uncaria tomentosa extracts compared to animals injected with vehicle only.