On the other hand, in SCLC STAT3 (down), EGFR, TP53, nuclear factor kappa B subunit 1 (NFKB1, down), Poly (ADP-ribose) polymerase 1 (PARP1, up), RHOA (down), UBE2l, VCAM1, fibronectin 1 (FN1) and RELA were recognized as hubs (Figure 4C). This evidence concerns the gene TP53 and small cell lung carcinoma.