Transfection of Polyinosinic:polycytidylic acid (shortly “Poly(I:C)”), which is a synthetic dsRNA that mimics viral infection [14], into 293T cells increased the IFN-β mRNA level and this increase was attenuated when nc886 was present (293T:nc886 as compared to 293T:vector) (Figure 1C). This evidence concerns the gene IFNB1 and viral infectious disease.