VEGFA and cancer: Other aptamer-gated NMOFs were developed following the protocol previously described including VEGF aptamer-functionalized DOX-loaded NMOFs for the release of a drug by over-expressed VEGF in cancer cells, [156] and thrombin aptamer-functionalized Apixaban-loaded NMOFs for the thrombin triggered release of the antiblood-clotting drug through the formation of the thrombin/thrombin aptamer complexes [157].