Investigating negative-regulated target genes, we found eight genes (ANKRD13C, ARL5A, ATL3, PAWR, PDCD6IP, SLC16A7, TFAM, UBP1) presenting a significant inverse correlation with miR-181a/b expression also in melanoma A375 sensitive cells (Supplementary Materials Table S1; Figure 5D). This evidence concerns the gene UBP1 and melanoma.