NDUFB11 and histiocytoid cardiomyopathy: They have occurred in 36% of LSDMCA1, in two individuals with point mutations in COX7B, and in two cases with point mutations in NDUFB11. Clinical features include atrioventricular septal defects, patent ductus arteriosum, coarctation of the aorta, patent foramen ovale, ventricular tachycardia, atrioventricular block, histiocytoid cardiomyopathy, poor contraction of the left ventricle, and eosinophilic cell infiltration.