COL7A1 and recessive dystrophic epidermolysis bullosa: Among disease subtypes, recessive dystrophic epidermolysis bullosa (RDEB) resulting from mutations in the type VII collagen (COL7A1) gene and subsequent lack of protein production can be alleviated by bone marrow-derived MSC (BM-MSC) EVs because they donate their own type VII collagen and induce host fibroblasts to produce this protein [76].