In this study we report for the first time the establishment of hiPSC-bKs derived from both ARCI patients, with previously unreported causal mutations in TGM1 and PNPLA1, respectively, and a TTD1 patient with mutations in ERCC2. Generated hiPSC-bKs displayed morphologies very similar to primary keratinocytes with high expression levels of basal keratins 14 and 5 (K14 and K5). The gene discussed is KRT14; the disease is trichothiodystrophy 1, photosensitive.