HLA-B and hypersensitivity reaction disease: For example, associations have been reported to exist between HLA-B*57:01 and abacavir-induced hypersensitivity reactions [31,32], HLA-B*15:02 and carbamazepine-induced SJS/TEN [33], and HLA-B*58:01 and allopurinol-induced SCARs (SJS/TEN and DIHS/DRESS) [34].