Examples include screening for HLA-B*57:01 to avoid abacavir hypersensitivity reactions, which is routinely performed in human immunodeficiency virus (HIV) patients, and for HLA*B15:02 to avoid carbamazepine-associated SJS/TEN in Asian populations, which could reduce the occurrence of SCARs [5,23]. This evidence concerns the gene HLA-B and toxic epidermal necrolysis.