In DIHS/DRESS, eosinophilia [1,2], increased plasma IL-5 levels [68], and increased serum levels of Th2-associated chemokines, including thymus and activation-regulated chemokine (TARC) [69,70,71,72] and macrophage-derived chemokine (MDC) [71], have been detected in the acute stage. Here, CCL22 is linked to Increased total eosinophil count.