FOS and breast carcinoma: Anita et al. reported that H2O2-induced migration of MCF-7 breast cancer cells was inhibited by G. lucidum through the marked inhibition of lipid peroxidation and phospho-Erk1/2 protein levels, which resulted in the downregulation of c-fos expression and inhibition of transcription factors AP-1 and NF-κB [105].